✦ LIBER ✦

Inhibition of hypoxia inducible factor 1α causes oxygen-independent cytotoxicity and induces p53 independent apoptosis in glioblastoma cells

✍ Scribed by Simon Dai; Mary Lin Huang; Chang Y Hsu; K.S.Clifford Chao

Book ID: 108435114
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 367 KB
Volume: 55
Category: Article
ISSN: 0360-3016
DOI: 10.1016/s0360-3016(02)04507-8

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Anoxia induces macrophage inhibitory cyt

Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1

✍ Albertoni, Michele; Shaw, Phillip H; Nozaki, Michimasa; Godard, Sophie; Tenan, M 📂 Article 📅 2002 🏛 Nature Publishing Group 🌐 English ⚖ 308 KB

Reactive oxygen species-mediated cyclin

Reactive oxygen species-mediated cyclin D1 degradation mediates tumor growth retardation in hypoxia, independently of p21cip1 and hypoxia-inducible factor

✍ Ji-Hong Lim; Yoon-Mi Lee; Yang-Sook Chun; Jong-Wan Park 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 476 KB

p53 upregulates cFLIP, inhibits transcri

p53 upregulates cFLIP, inhibits transcription of NF-κB-regulated genes and induces caspase-8-independent cell death in DLD-1 cells

✍ Bartke, Till; Siegmund, Daniela; Peters, Nathalie; Reichwein, Monica; Henkler, F 📂 Article 📅 2001 🏛 Nature Publishing Group 🌐 English ⚖ 344 KB

The novel heterodinucleoside dimer 5-FdU

The novel heterodinucleoside dimer 5-FdU-NOAC is a potent cytotoxic drug and a p53-independent inducer of apoptosis in the androgen-independent human prostate cancer cell lines PC-3 and DU-145

✍ R.M.C. Cattaneo-Pangrazzi; H. Schott; R.A. Schwendener 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 323 KB 👁 2 views

BACKGROUND. We analyzed the cytotoxic properties of the new heterodinucleoside phosphate dimer 5-FdU-NOAC, which is composed of the cytotoxic drugs 5-FdU and N 4octadecyl-1-␤-D-arabinofuranosylcytosine (NOAC) against human prostate tumor cells. METHODS. 5-FdU-NOAC effects on cell proliferation, cell

Inhibition of Rel/Nuclear Factor-κB sign

Inhibition of Rel/Nuclear Factor-κB signaling in skin results in defective DNA damage-induced cell cycle arrest and Ha-ras- and p53-independent tumor development

✍ van Hogerlinden, Max; Auer, Gert; Toftgård, Rune 📂 Article 📅 2002 🏛 Nature Publishing Group 🌐 English ⚖ 643 KB

Inhibition of p38α MAPK enhances proteas

Inhibition of p38α MAPK enhances proteasome inhibitor-induced apoptosis of myeloma cells by modulating Hsp27, Bcl-XL, Mcl-1 and p53 levels in vitro and inhibits tumor growth in vivo

✍ Navas, T A; Nguyen, A N; Hideshima, T; Reddy, M; Ma, J Y; Haghnazari, E; Henson, 📂 Article 📅 2006 🏛 Nature Publishing Group 🌐 English ⚖ 679 KB