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Inhibition of Huntingtin Synthesis by Antisense Oligodeoxynucleotides

✍ Scribed by Christine Nellemann; Kathrine Abell; Anne Nørremølle; Thomas Løkkegaard; Bjarke Naver; Carsten Röpke; Jørgen Rygaard; Sven Asger Sørensen; Lis Hasholt

Book ID
115637662
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
336 KB
Volume
16
Category
Article
ISSN
1044-7431

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Inhibition of ornithine decarboxylase an
Inhibition of ornithine decarboxylase and S-adenosylmethionine decarboxylase synthesis by antisense oligodeoxynucleotides
✍ Rentala Madhubala; Anthony E. Pegg 📂 Article 📅 1992 🏛 Springer 🌐 English ⚖ 374 KB

Oligodeoxynucleotides 18 nucleotides in length having sequences complementary to regions spanning the initiation codon regions of ornithine decarboxylase or S-adenosylmethionine decarboxylase mRNAs were tested for their ability to inhibit translation of these mRNAs. In reticulocyte lysates, a strong