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Growth inhibition of pancreatic tumor cells by modified antisense oligodeoxynucleotides

✍ Scribed by Alexander Fiedler; Christoph Knorre; Yvonne Franke; Doris Henne-Bruns; Bernd Kremer; Jutta Lüttges; Martin Maier; Michael Gerster; Konrad Bleicher; Ernst Bayer; H. Kalthoff


Publisher
Springer
Year
1998
Tongue
English
Weight
231 KB
Volume
383
Category
Article
ISSN
1435-2451

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## Abstract In this study, a novel nonviral gene delivery system, which could enhance the inhibition effect of antisense oligonucleotides (ASODN) against the tumor cells, was developed. The polycation liposomes (PCLs) were prepared using the film hydration method with dioleoylphosphatidylethanolami