Inhibition of human renin by concanavalin A
β Scribed by Hiroko Tanaka; Kunio Hiwada; Tatsuo Kokubu
- Book ID
- 115774255
- Publisher
- Elsevier Science
- Year
- 1978
- Tongue
- English
- Weight
- 139 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0006-2952
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Renin substrate, the serum prohormone of angiotensin, is a glycoprotein which is shown to bind to concanavalin A. This interaction permits the use of lectin affinity chromatography in overcoming a major problem in the protein's purification, namely the separation of renin substrate from albumin and
## Abstract The protein concanavalin A (Con. A) that binds to glucose or mannoseβlike sites on the cell surface membrane, and glycoproteins from wheat germ and soybean that bind to NβacetylβDβglucosamineβlike sites and NβacetylβDβgalactosamineβlike sites, respectively, agglutinate cells of the asci