Inhibition of human parainfluenza virus type 1 sialidase by analogs of 2-deoxy-2,3-didehydro-N-acetylneuraminic acid
โ Scribed by Takashi Suzuki; Kiyoshi Ikeda; Noriko Koyama; Chika Hosokawa; Toshihiro Kogure; Tadanobu Takahashi; Kazuya I.-P. Jwa Hidari; Daisei Miyamoto; Kiyoshi Tanaka; Yasuo Suzuki
- Book ID
- 110322955
- Publisher
- Springer US
- Year
- 2001
- Tongue
- English
- Weight
- 161 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1573-4986
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The biochemistry and synthesis of sialidase inhibitors, in particular influenza virus sialidase inhibitors, has been of great interest to us [1][2][3]. The synthesis of a number of S-acetamido-2,6-anhydro-3,5-dideoxy-o-glycero-o-galacto-non-2-enonic acid (Neu5Ac2en, 1) analogues has received conside
Thl: perawtylstcd mcthyl cstcr dcrivativcs of 7-rpi-i-NeuSAc (ta), H-epi-NeuSAc (3 a), and 7.8-bis-epi-NcuSAc (4 a) wcrc transformed hy trimcihylsilyl trifluoromethanesulronale into the corrcsponding 2-cieoxy-2,3-didehydro derivatives 2b-4 b. As minor products the 4.5-osazolino derivatives 5 b rind