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Inhibition of hepatitis B virus replication by targeted pretreatment of complexed antisense DNA in vitro

โœ Scribed by K Nakazono; Y Ito; CH Wu; GY Wu

Book ID
118686225
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
310 KB
Volume
23
Category
Article
ISSN
0270-9139

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Inhibition of hepatitis B virus replicat
Inhibition of hepatitis B virus replication by targeted pretreatment of complexed antisense DNA in vitro
โœ K Nakazono; Y Ito; C H Wu; G Y Wu ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 310 KB ๐Ÿ‘ 1 views

We have shown that antisense oligonucleotides can be targeted to hepatitis B virus (HBV)-infected cells, resulting in specific inhibition of viral protein synthesis and replication in vitro. The targeting system was based on the internalization of DNA complexes by highly selective receptors for gala