Inhibition of hepatitis B virus DNA poly
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T Shaw; S S Mok; S A Locarnini
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Article
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1996
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John Wiley and Sons
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English
β 286 KB
π 2 views
The deoxyguanosine analog penciclovir (PCV; 9-[4-hydroxy-3-hydroxymethyl-but-1-yl]guanine), has shown potent antiviral activity against herpes viruses and hepadnaviruses. Efficacy against chronic hepatitis B virus (HBV) infection has been demonstrated in an animal model and in recent clinical trials