The deoxyguanosine analog penciclovir (PCV; 9-[4-hydroxy-3-hydroxymethyl-but-1-yl]guanine), has shown potent antiviral activity against herpes viruses and hepadnaviruses. Efficacy against chronic hepatitis B virus (HBV) infection has been demonstrated in an animal model and in recent clinical trials
Inhibition of hepatitis B virus DNA polymerase by enantiomers of penciclovir triphosphate and metabolic basis for selective inhibition of HBV replication by penciclovir
✍ Scribed by T Shaw; SS Mok; SA Locarnini
- Book ID
- 118686438
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 291 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0270-9139
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