An inhibitory effect of 3'-azido-3'-deoxythymidine triphosphate on hepatitis B virus DNA polymerase was found. No effect was seen by its threo analog. The effect was detected at and above a concentration of 0.05 microM. The inhibition of DNA polymerase activity was the same in ten different strains
Inhibition of hepatitis-B-virus DNA polymerase by phosphonoformate: Studies on its mode of action
✍ Scribed by Georg Hess; Wolfgang Arnold; Karl-Herrmann Meyer Büschenfelde
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 360 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0146-6615
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