NADPH-cytochrome c (P-450) reductase from liver microsomes of phenobarbital-treated rats has been purified in a single step by affinity chromatography on agarose-hexane-adenosine 2',5'-diphosphate. As determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, enzyme assay, and radioimm
β¦ LIBER β¦
Inhibition of hepatic microsomal NADPH-cytochrome C (P-450) reductase activity in gari-fed rats
β Scribed by Onyechi Obidoa; Gladys U. Uzoka
- Publisher
- Springer US
- Year
- 1985
- Tongue
- English
- Weight
- 533 KB
- Volume
- 35
- Category
- Article
- ISSN
- 1573-9104
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## Abstract Aristolochic acid (AA), a naturally occurring nephrotoxin and carcinogen, has been associated with the development of urothelial cancer in humans. Understanding which human enzymes are involved in AA activation and/or detoxication is important in the assessment of an individual's suscep