๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Inhibition of heme synthesis alters Amyloid Precursor Protein processing

โœ Scribed by Luisa Benerini Gatta; Massimiliano Vitali; Rosanna Verardi; Paolo Arosio; Dario Finazzi


Publisher
Springer
Year
2008
Tongue
English
Weight
472 KB
Volume
116
Category
Article
ISSN
1435-1463

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Altered processing of a mutant amyloid p
โœ Boyu Zhao; S. S. Sisodia; J. W. Kusiak ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 1009 KB

Altered proteolysis of the amyloid precursor protein (APP) may play an important role in Alzheimer disease (AD). To better understand the role of mutant APP in the pathogenesis of the disease, we stably overexpressed the mutant APP717F approximately twofold vs. the endogenous wild-type gene in sever

Effect of aluminium on expression and pr
โœ D. Neill; A. Leake; D. Hughes; A.B. Keith; G.A. Taylor; D. Allsop; B.K. Rima; C. ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 948 KB

The environmental agent aluminium has been extensively investigated for a potential role in the aetiology of Alzheimer's disease. Despite many investigations there is at present no definite proof for any involvement. If aluminium is involved it is possible that its action is mediated through interac

Intracellular trafficking of the ฮฒ-secre
โœ Pei Zhi; Cheryl Chia; Paul A. Gleeson ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 354 KB

The main component of the amyloid plaques found in the brains of those with Alzheimer's disease (AD) is a polymerized form of the b-amyloid peptide (Ab) and is considered to play a central role in the pathogenesis of this neurodegenerative disorder. Ab is derived from the proteolytic processing of t