Lym-I is a murine IgG2, monoclonal antibody (MAb) that is B-cell specific but has greater avidity for malignant B cells when compared with normal B lymphocytes. It was originally produced by immunizing mice with nuclei of cultured cells from a patient with Burkitt's lymphoma. Ten patients with progr
Inhibition of Hematopoiesis in Vitro with the Lym-1 Monoclonal Antibody
β Scribed by D. TUCK; M. SILVA; S. SORBA; A. GUHA; K. I. ABRAHAM; D. SCHOCHAT; N. DAINIAK
- Book ID
- 119865586
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 301 KB
- Volume
- 628
- Category
- Article
- ISSN
- 0890-6564
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Lym-1) or its fragment F(ab')2 to produce two new radiopharmaceuticals. Immunoreactivity of the Lym-1, specific for B cell lymphoma, was not affected by the coupling reaction for 1.0 and 4.3 CITC molecules per whole antibody and 3.0 CITC molecules per F(ab')2 fragment. Both retained in excess of 90%