## Background: Hormones like bombesin (bn)/gastrin-releasing peptide (grp) and luteinizing hormone-releasing hormone (lh-rh) and growth factors such as epidermal growth factor (egf) might be involved in the relapse of prostate cancer under androgen ablation therapy. interference with receptors for
Inhibition of growth of androgen-independent DU-145 prostate cancer in vivo by luteinising hormone-releasing hormone antagonist cetrorelix and bombesin antagonists RC-3940-II and RC-3950-II
β Scribed by A. Jungwirth; J. Pinski; G. Galvan; G. Halmos; K. Szepeshazi; R.Z. Gai; K. Groot; M. Vadillo-buenfil; A.V. Schally
- Book ID
- 117663823
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 966 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0959-8049
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## Background: Metastatic or recurrent renal cell carcinoma (rcc) is a therapeutic challenge because it is resistant to chemotherapy and external radiotherapy. no uniformly effective therapeutic agents are available for the management of patients with rcc. hormones and growth factors may play a rol
## BACKGROUND. The growth of breast carcinoma is promoted by autocrine growth factors such as the bombesin (BN)-like peptides and epidermal growth factor (EGF). The stimulatory action of BN-like peptides can be blocked by the use of BN/gastrin-releasing peptide (GRP) antagonists. ## METHODS. The