Resistance of transformed mouse keratino
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Vladimir S. Spiegelman; Irina V. Budunova; Steve Carbajal; Thomas J. Slaga
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Article
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1997
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John Wiley and Sons
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English
โ 327 KB
Glucocorticoid hormones are strong inhibitors of normal keratinocyte proliferation, but established mouse skin papillomas and carcinomas become resistant to these hormones. The biological effect of glucocorticoids is mediated through a highly specific glucocorticoid receptor (GR). To study the possi