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Inhibition of gap-junctional intercellular communication by outdoor and indoor airborne particulate matter

✍ Scribed by Heussen, G.A.H.; Alink, G.M.

Book ID: 122023639
Publisher: Elsevier Science
Year: 1994
Tongue: English
Weight: 536 KB
Volume: 72
Category: Article
ISSN: 0378-4274
DOI: 10.1016/0378-4274(94)90014-0

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## Abstract The phorbol ester, 12‐__O__‐tetradecanoylphorbol‐13‐acetate (TPA), is a potent inhibitor of gap junctional intercellular communication (GJIC). This inhibition requires activation of protein kinase C (PKC), but the events downstream of this kinase are not known. Since PKC can activate ex