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Inhibition of extracellular signal-regulated kinase 1/2 augments nitric oxide production in lipopolysaccharide-stimulated RAW264.7 macrophage cells

✍ Scribed by Naoki Koide; Hiroyasu Ito; Mya Mya Mu; Tsuyoshi Sugiyama; Ferdaus Hassan; Shamima Islam; Isamu Mori; Tomoaki Yoshida; Takashi Yokochi


Book ID
108131096
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
282 KB
Volume
45
Category
Article
ISSN
0928-8244

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Pyrrolidinone diterpenoid from Isodon ex
✍ Seong Su Hong; Seon A Lee; Nahyun Kim; Ji Sang Hwang; Xiang Hua Han; Mi Kyeong L πŸ“‚ Article πŸ“… 2011 πŸ› Elsevier Science 🌐 English βš– 214 KB

A new pyrrolidinone diterpenoid, excisusin F (1), was isolated from the aerial parts of Isodon excisus (Lamiaceae), together with four known compounds, and their structures were determined mainly by NMR (1D and 2D) and mass spectrometry. Excisusin F (1) and inflexarabdonin E (3) showed potent inhibi