Inhibition of experimental lung metastases of Lewis lung carcinoma cells by chemically modified heparin with reduced anticoagulant activity
β Scribed by Yasuo Yoshitomi; Hayao Nakanishi; Yuri Kusano; Seiichi Munesue; Kayoko Oguri; Masae Tatematsu; Ikuo Yamashina; Minoru Okayama
- Book ID
- 116333003
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 445 KB
- Volume
- 207
- Category
- Article
- ISSN
- 0304-3835
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We have examined the effects of the synthetic matrix metalloproteinase inhibitor, batimastat (BB-94) and the angiotensin-converting enzyme inhibitor, captopril, on metalloproteinase activity of murine Lewis-lung-carcinoma cells (3LL) in vitro, and on local growth and lung metastasis of the same tumo
## Abstract The possibility of inhibiting local tumor growth (experimental and spontaneous lung metastases) of the selected highlyβmetastatic Syrian hamster sarcoma of STHEβLM^8^ subline by means of nonβactivated syngeneic and allogeneic spleen, bone marrow (BMC) and peritoneal exudate (PEC) cells