Selective inhibition of spontaneous pulm
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Tohru Ishikawa; Masako Ura; Taeko Yamamoto; Yutaka Tanaka; Hideo Ishitsuka
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Article
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1995
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John Wiley and Sons
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French
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5'-deoxy-5-fluorouridine (5'-FUdR) is a cytostatic that is biotransformed to 5-fluorouracil(5-FUra) by pyrimidine nucleoside phosphorylase (PyNPase), the expression of which is up-regulated by tumor necrosis factor QL (TNFa), interleukin-I a (ILla) and interferon 'y (IFNy). In Lewis lung carcinoma (