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Inhibition of eucaryotic DNA polymerases by phosphonoacetate and phosphonoformate

✍ Scribed by Carol L.K. Sabourin; John M. Reno; John A. Boezi


Book ID
115703554
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
602 KB
Volume
187
Category
Article
ISSN
0003-9861

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Differential inhibition of DNA polymeras
✍ Miriam Margalith; Haya Falk; Amos Panet πŸ“‚ Article πŸ“… 1982 πŸ› Springer 🌐 English βš– 439 KB

Three potential inhibitors of reverse transcriptase activities, phosphonoformate (PF), phosphonoacetate (PAA), and ethyl-diethyl phosphonoformate (Et-PF), were compared in this study. Only PF was found to inhibit the DNA polymerase activity of the purified reverse transcriptase of Moloney murine leu