Multiple mechanisms in the regulation of
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Dennis R. Koop; Daniel J. Tierney
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Article
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1990
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John Wiley and Sons
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English
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## Abstract Cytochrome P450IIE1 is involved in the metabolic activation of many xenobiotics involved with human toxicity. In particular, cellular concentrations of P450IIE1 are significantly induced by the most widely abused drug in our society today, alcohol. As a result, the synthesis and degrada