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Inhibition of ethanol-inducible cytochrome P 450IIE1 by 3-amino-1,2,4-triazole

✍ Scribed by Koop, Dennis R.


Book ID
121318796
Publisher
American Chemical Society
Year
1990
Tongue
English
Weight
963 KB
Volume
3
Category
Article
ISSN
0893-228X

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✍ Dennis R. Koop; Daniel J. Tierney πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 881 KB

## Abstract Cytochrome P450IIE1 is involved in the metabolic activation of many xenobiotics involved with human toxicity. In particular, cellular concentrations of P450IIE1 are significantly induced by the most widely abused drug in our society today, alcohol. As a result, the synthesis and degrada