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Inhibition of DNA Repair and Sensitization of Cisplatin in Human Ovarian Carcinoma Cells by Interleukin-1α

✍ Scribed by M.N. Benchekroun; R. Parker; E. Reed; B.K. Sinha

Book ID
115573421
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
305 KB
Volume
195
Category
Article
ISSN
0006-291X

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## Abstract Human ovarian carcinoma exhibits a spectrum of responses to treatment with cisplatin, ranging from marked sensitivity to relative resistance. Variations in the efficiency with which cells repair cisplatin‐DNA adducts may in part determine cisplatin sensitivity. We have investigated the