In vitro kinetics of the rat brain succi
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V. Lokanatha; P. Sailaja; W. Rajendra
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Article
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1999
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John Wiley and Sons
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English
β 82 KB
π 2 views
Brain succinate dehydrogenase (SDH) activity was inhibited by in vitro hexachlorophene (HCP) with a half inhibitory concentration (IC 50 ) of 0.65 β«β¬ 10 β«3β¬ M. The HCP exerted noncompetitive inhibition at 0.5 mM (Ο½IC 50 ), uncompetitive inhibition at 0.65 mM (IC 50 ), and mixed-type inhibition at 0.