Inhibition of cyclophilin function in HIV-I infection by cyclosporin A
β Scribed by Ralf Huss
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 285 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0167-5699
No coin nor oath required. For personal study only.
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**It no longer takes two**. We report on cyclosporin A (CsA) derivatives that inhibit calcineurin protein phosphatase activity without first forming a binary complex with cyclophilin 18. Furthermore, these derivatives are rapid binding inhibitors for cyclophilin 18, whereas CsA is a slow binding inh