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Inhibition of COX-2 by celecoxib enhances glucocorticoid receptor function

✍ Scribed by Hu, F; Wang, X; Pace, T W W; Wu, H; Miller, A H


Book ID
110059928
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
86 KB
Volume
10
Category
Article
ISSN
1359-4184

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## Abstract The P‐glycoprotein (p170, P‐gp) encoded by human __MDR1__ gene functions as a pump to extrude anticancer drugs from cancer cells. Over‐expression of p170 is closely related to primary and induced drug resistance phenotype of tumor cells. Recent studies have demonstrated that expression