Inhibition of cholesteryl ester transfer protein activity: A new therapeutic approach to raising high-density lipoprotein
β Scribed by Daniel J. Rader
- Book ID
- 107533810
- Publisher
- Current Science Inc.
- Year
- 2004
- Tongue
- English
- Weight
- 457 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1523-3804
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π SIMILAR VOLUMES
Therapeutic strategies to increase high-density lipoprotein (HDL) to treat or prevent vascular disease include the use of cholesteryl-ester transfer protein (CETP) inhibitors. Here, we show, to the best of our knowledge for the first time, that addition of CETP to HDL enhances the ability of HDL to
High plasma concentrations of high-density lipoprotein (HDL) cholesterol are a powerful indicator of low vascular risk. By decreasing HDL cholesterol, cholesteryl ester transfer protein (CETP) could perhaps constitute an atherogenic protein. We measured HDL cholesterol and HDL subfractions and quant