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Inhibition of cholesterol synthesis by oxygenated sterols

โœ Scribed by Andrew A. Kandutsch; Harry W. Chen


Book ID
112772154
Publisher
Springer-Verlag
Year
1978
Tongue
English
Weight
350 KB
Volume
13
Category
Article
ISSN
0024-4201

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Regulation of sterol synthesis in cultur
โœ A. A. Kandutsch; H. W. Chen ๐Ÿ“‚ Article ๐Ÿ“… 1975 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 672 KB

Sterol synthesis in liver in vivo is regulated at the site of the reaction catalyzed by 3-hydroxy-3-methylglutaryl-CoA reductase through a feedback system thought to involve either cholesterol or one or more of the products of its metabolism. Cholesterol feeding results in repression of the synthesi