Tumor metastasis is the primary cause of death for cancer patients. The metastatic cascade requires successful tumor cell invasion into and through vascular and parenchymal barriers. We have shown that autocrine motility factor (AMF, autotaxin) and the insulin-like growth factors (IGFs) induce tumor
Inhibition of chemotactic migration of human neutrophilic granulocytes by recombinant human granulocyte-macrophage colony-stimulating factor
β Scribed by Exkhard Kownatzki; Ekke Liehl; Heinz Aschauer; Sibylle Uhrich
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 344 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0162-3109
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## Abstract Twenty children 1β17 (median, 5.5) years of age received GMβCSF during chemotherapyβinduced neutropenia at the dose of 5 ΞΌg/kg/day, continued until the absolute neutrophil count (ANC) exceeded 500 Γ 10^6^/liter. Twelve children with solid tumors received GMβCSF after courses of conventi
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