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Inhibition of cell growth and of purine biosynthesis by allopurinol and 4-aminopyrazolo(3,4-d)pyrimidine— a comparative study

✍ Scribed by Kumiko Iwamoto; David W. Martin Jr.


Book ID
115772328
Publisher
Elsevier Science
Year
1974
Tongue
English
Weight
658 KB
Volume
23
Category
Article
ISSN
0006-2952

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## Abstract A series of pyrazolo[3,4‐d]pyrimidines, previously found to be Src inhibitors, was tested for their ability to inhibit proliferation of three Bcr‐Abl‐positive human leukemia cell lines (K‐562, KU‐812, and MEG‐01), on the basis of the experimental evidence that various Src inhibitors are