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Inhibition of purine biosynthesis de novo and of Ehrlich ascites tumor cell growth by 6-methylmercaptopurine ribonucleoside

✍ Scribed by Geraldine D. Shantz; Lydia J. Fontenelle; J.Frank Henderson

Book ID: 115771177
Publisher: Elsevier Science
Year: 1972
Tongue: English
Weight: 300 KB
Volume: 21
Category: Article
ISSN: 0006-2952
DOI: 10.1016/0006-2952(72)90115-3

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## Abstract ## Background Vascular endothelial growth factor (VEGF) is known to play a major role in angiogenesis. A soluble form of Flt‐1, a VEGF receptor, is potentially useful as an antagonist of VEGF, and accumulating evidence suggests the applicability of sFlt‐1 in tumor suppression. In the p