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Inhibition of cathepsin B and papain by peptidyl α-keto esters, α-keto amides, α-diketones, and α-keto acids

✍ Scribed by Lain-Yen Hu; Robert H. Abeles


Book ID
115708494
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
427 KB
Volume
281
Category
Article
ISSN
0003-9861

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Oxidation of alkynyl ethers and -amines with iodosylbenzene in presence of Rucatalysts affords a-keto esters and a-keto amides in 44-84% yield. These conversions can also be effected with RuO,. Oxidations based on iodosylbenzene are of current interest in connection with model studies for peroxidase