𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Inhibition of catechol-O-methyltransferase activity by two novel disubstituted catechols in the rat

✍ Scribed by Erkki Nissinen; Inge-Britt Lindén; Eija Schultz; Seppo Kaakkola; Pekka T. Männistö; Pentti Pohto


Book ID
115881818
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
499 KB
Volume
153
Category
Article
ISSN
0014-2999

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Inhibition of human erythrocyte and gast
✍ E. Schultz; S. Tarpila; A.-C. Bäckström; A. Gordin; E. Nissinen; P. Pohto 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 367 KB

The effect of increasing single oral doses of the novel catechol-O-methyltransferase (COMT) inhibitor, nitecapone, on enzyme activity in red cells (RBC) and gastroduodenal COMT activity has been studied in healthy male volunteers. A dose-dependent decrease in RBC COMT activity was seen in all cases