Inhibition of calpain attenuates encephalitogenicity of MBP-specific T cells
โ Scribed by Mary K. Guyton; Saurav Brahmachari; Arabinda Das; Supriti Samantaray; Jun Inoue; Mitsuyoshi Azuma; Swapan K. Ray; Naren L. Banik
- Book ID
- 111183600
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 812 KB
- Volume
- 110
- Category
- Article
- ISSN
- 0022-3042
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Naive LEW rats and animals that have recovered from active or adoptive EAE contain a subset of T cells that inhibit EAE in secondary recipients and are lytic for MBP-reactive T cell lines in culture. Here we explore various features of these regulatory T cell populations (RTC) with respect to (1) th
Myelin basic protein (MBP) is a well-characterized autoantigen potentially involved in the pathogenesis of the most common human demyelinating disease of the central nervous system (CNS), multiple sclerosis (MS). It is known that MBP-specific T-cell responses differ widely among different individual