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Inhibition of beta-amyloid toxicity by short peptides containing N-methyl amino acids

✍ Scribed by Cruz, M. ;Tusell, J.M. ;Grillo-Bosch, D. ;Albericio, F. ;Serratosa, J. ;Rabanal, F. ;Giralt, E.


Book ID
110893783
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
170 KB
Volume
63
Category
Article
ISSN
1397-002X

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Synthesis of neoglycopeptides by chemose
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A novel N%-methyl-aminooxy amino acid has been designed, synthesized, and successfully incorporated into peptides using standard solid-phase peptide synthesis procedures. Reaction of these peptides with native reducing sugars yields neoglycopeptides via a chemoselective reaction with the aminooxy si