The effects of putrescine on the incidence and number of colon tumors induced by azoxymethane, and on the labelling index and the activity of ornithine decarboxylase (ODC) in the colon mucosa were investigated in Wistar rats. Rats re- ceived 10 weekly injections of 7.4 mg/kg body weight of azoxymeth
Inhibition of Azoxymethane-induced Colon Carcinogenesis in Rat by Green Tea Polyphenol Fraction
β Scribed by Yamane, Testsuro ;Hagiwara, Nobuyuki ;Tateishi, Masaya ;Akachi, Shigemitsu ;Kim, Mujo ;Okuzumi, Jyunichi ;Kitao, Yoshitaka ;Inagake, Masao ;Kuwata, Katsuya ;Takahashi, Toshio
- Book ID
- 108579243
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1991
- Tongue
- English
- Weight
- 230 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0910-5050
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MATERIAL AND METHODS ## Animals Sixty male Wistar rats were received from SLC (Shizuoka, Japan) at 45 days of age and maintained in isolation for 10 days. The animals were housed in suspended cages with wire-mesh bottoms in animal quarters at controlled tempera-3To whom correspondence and reprint
## Abstract Tea, one of the most widely consumed beverages worldwide, has been shown to have antiβcancer activity in various cancers including colon cancer. It has been demonstrated that overexpression of the inducible isoform of cyclooxygenase (COXβ2) occurs during colon tumorigenesis and inhibiti
## Abstract The modifying effect of dietary administration of the polyphenolic antioxidant flavonoid silymarin, isolated from milk thistle [__Silybum marianum__ (L.) Gaertneri], on AOMβinduced colon carcinogenesis was investigated in male F344 rats. In the shortβterm study, the effects of silymarin
The effect of thyroxine (T4) on the incidence, number and histology of colon tumors induced by azoxymethane (AOM), and on the labeling index of colon mucosa were investigated in Wistar rats. Rats were given AOM by injection once a week for 10 weeks, together with T, in depot form until the end of th