The effects of putrescine on the incidence and number of colon tumors induced by azoxymethane, and on the labelling index and the activity of ornithine decarboxylase (ODC) in the colon mucosa were investigated in Wistar rats. Rats re- ceived 10 weekly injections of 7.4 mg/kg body weight of azoxymeth
Inhibition of azoxymethane-induced experimental colon carcinogenesis in wistar rats by 6-hydroxydopamine
β Scribed by Masaharu Tatsuta; Hiroyasu Iishi; Miyako Baba; Haruo Taniguchi
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- French
- Weight
- 505 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0020-7136
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β¦ Synopsis
MATERIAL AND METHODS
Animals
Sixty male Wistar rats were received from SLC (Shizuoka, Japan) at 45 days of age and maintained in isolation for 10 days. The animals were housed in suspended cages with wire-mesh bottoms in animal quarters at controlled tempera-3To whom correspondence and reprint requests should be addressed.
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