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Inhibition of acetylcholinesterase by the anticancer prodrug CPT-11

โœ Scribed by Janice L. Hyatt; Lyudmila Tsurkan; Christopher L. Morton; Kyoung J.P. Yoon; Michal Harel; Boris Brumshtein; Israel Silman; Joel L. Sussman; Randy M. Wadkins; Philip M. Potter


Book ID
113517235
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
167 KB
Volume
157-158
Category
Article
ISSN
0009-2797

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Inhibition of spontaneous and experiment
โœ Takeshi Matsuzaki; Teruo Yokokura; Masahiko Mutai; Takashi Tsuruo ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Springer ๐ŸŒ English โš– 427 KB

The antimetastatic effect of a new water-soluble derivative of camptothecin, 7-ethyl-10-(4-(1-piperidino)-1-piperidino) carbonyloxy-camptothecin (CPT-11), were examined in several metastatic murine tumor systems. Intravenous (i.v.) injection of CPT-11 into BALB/c mice inhibited lung metastasis by i.