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Inhibition of acetaminophen hepatotoxicity by acetaldehyde in the rat

✍ Scribed by Jian, Liu; Chifumi, Sato; Happei, Miyakawa; Toshinori, Kamiyama; Kazuo, Tajiri; Mieko, Goto; Fumiaki, Marumo

Book ID
123218929
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
532 KB
Volume
62
Category
Article
ISSN
0378-4274

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Acetaldehyde, the first metabolite of ethanol oxidation, has been proposed as a major initiating factor in ethanol-induced liver injury. The aims of this study were to examine whether acetaldehyde is absorbable from the digestive tract and whether, when delivered chronically in drinking water, it is