Inhibition by verapamil of cholecystokinin-enhancement of pancreatic carcinogenesis induced by azaserine in Wistar rats
โ Scribed by Akihiko Nakaizumi; Hiroyuki Uehara; Miyako Baba; Hiroyasu Iishi; Masaharu Tatsuta
- Book ID
- 116123531
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 426 KB
- Volume
- 105
- Category
- Article
- ISSN
- 0304-3835
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The effects of galanin on pancreatic carcinogenesis induced by azaserine and on the norepinephrine concentration in the pancreas were investigated in male Wistar rats. Rats were given weekly injections of 10 mg/kg body weight of azaserine for 25 weeks and 8 g/kg body weight of galanin in depot form
MATERIAL AND METHODS ## Animals Sixty male Wistar rats were received from SLC (Shizuoka, Japan) at 45 days of age and maintained in isolation for 10 days. The animals were housed in suspended cages with wire-mesh bottoms in animal quarters at controlled tempera-3To whom correspondence and reprint