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Inhibition by transforming growth factor (34-43)-α, a TGF-α antagonist, of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats

✍ Scribed by Tatsuta, M; Iishi, H; Baba, M; Hirasawa, R; Iseki, K; Yano, H; Sakai, N; Uehara, H; Nakaizumi, A


Book ID
109838627
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
752 KB
Volume
78
Category
Article
ISSN
0007-0920

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The effect of tyrosine methyl ester (TME) on the incidence, number, and histological types of gastric cancers induced by N-methyl-N'-nitro-N-nitroroguanidine (MNNG) was investigated in male Wistar rats. Rats were subcutaneously given TME, 5 I 2 mg/kg body weight, every other day after 20 weeks of or