## Abstract We have attempted to determine what host mechanisms are responsible for inducing a rapid decrease in the number of Friend leukemia cells (FLC) in the peritoneal cavity of interferonβtreated mice. By injecting radiolabelled FLC, we showed that there was a greater loss of radioactivity fr
Inhibition by interferon (IFN) of the development of hepatic and splenic metastases in mice: role of host mechanisms
β Scribed by I. Gresser; F. Belardelli; C. Maury; C. Carnaud; D. Woodrow
- Book ID
- 115883699
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 87 KB
- Volume
- 183
- Category
- Article
- ISSN
- 0014-2999
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DBAl2 mice were injected i.v. with IFN alp-resistant 3C I 8 Friend erythroleukemia cells (FLC) which metastasize to the liver and spleen. IFN d p treatment of FLC-injected mice increased their survival time and these mice developed a resistance to a second challenge with FLC. The efficacy of IFN d p
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