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Inhibition by anti-HLA class II monoclonal antibodies of monocyte-dependent T cell proliferation induced by monoclonal antibody OKT3

✍ Scribed by Giuseppina Ruggiero; Ciro Manzo; Silvia Fontana; Giuseppe Scala; Giuseppe Pirozzi; Soldano Ferrone; Serafino Zappacosta


Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
786 KB
Volume
17
Category
Article
ISSN
0014-2980

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Human in vivo antigenic modulation induc
✍ Lucienne Chatenoud; Marc F. Baudrihaye; Henri Kreis; Gideon Goldstein; John Schi πŸ“‚ Article πŸ“… 1982 πŸ› John Wiley and Sons 🌐 English βš– 345 KB

## Abstract The anti‐pan T cell monoclonal antibody OKT3 was administered daily for 2 weeks in four human renal allograft recipients. The antibody induced a dramatic and immediate depletion of peripheral T cells followed by an __in vivo__ antigenic modulation of the OKT3‐defined membrane antigen: a