Human in vivo antigenic modulation induc
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Lucienne Chatenoud; Marc F. Baudrihaye; Henri Kreis; Gideon Goldstein; John Schi
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Article
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1982
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John Wiley and Sons
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English
β 345 KB
## Abstract The antiβpan T cell monoclonal antibody OKT3 was administered daily for 2 weeks in four human renal allograft recipients. The antibody induced a dramatic and immediate depletion of peripheral T cells followed by an __in vivo__ antigenic modulation of the OKT3βdefined membrane antigen: a