were prepared by using a sulfur trioxide complex (Aldrich, Milwaukee, Wis.) as described previously (Donovon, J. M. et al., Gastroenterology 1984; 84:1046, Abstract). When sulfation was complete (all the hydroxyl groups were sulfated), the purity of sulfated bile acids was better than 96% as checked
Inhibition and induction of bile acid synthesis by ketoconazole effects on bile formation in the rat
β Scribed by Folkert Kuipers; Rick Havinga; Christine M. G. Huijsmans; Roel J. Vonk; Hans M. G. Princen
- Book ID
- 112777813
- Publisher
- Springer-Verlag
- Year
- 1989
- Tongue
- English
- Weight
- 550 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0024-4201
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Bile acid synthesis is thought to be regulated by a negative feedback mechanism which is presumably dependent upon the flux of bile acids in the enterohepatic circulation. To characterize further the role of bile acids in regulation of bile acid synthesis, we have administered pure taurine or glycin
Bile acid synthesis is believed to be regulated by bile salts returning to the liver via the portal vein and suppressing cholesterol 7a-hydroxylase, the rate-limiting enzyme in the bile acid biosynthesis pathway. In order to characterize the relative effectiveness of bile salts in regulating bile ac