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Inhibiting 5α-Reductase Isoenzymes for Prostate Cancer


Book ID
122637993
Publisher
Lippincott Williams and Wilkins
Year
2008
Tongue
English
Weight
22 KB
Volume
179
Category
Article
ISSN
0022-5347

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Differential expression of 5α-reductase
✍ Bonkhoff, Helmut; Stein, Ute; Aumüller, Gerhard; Remberger, Klaus 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 658 KB

BACKGROUND. Steroid 5a-reductase is essential for the intracellular accumulation of dihydrotestosterone (DHT), which mediates androgen effects on target tissue. METHODS. In the present study, we describe the differential expression and cellular localization of 5a-reductase 1 and 2 isoenzymes in the