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Inhibin A and inhibin pro-αC in patients with hydatidiform mole

✍ Scribed by T. Kato; F. Koma; H. Matsui; K. Seki; S. Sekiya


Book ID
117124891
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
164 KB
Volume
70
Category
Article
ISSN
0020-7292

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Using two enzyme-linked immunosorbent assays specific for inhibin A and pro-C inhibin, levels of the two proteins were assessed in maternal serum from 43 Down syndrome and 300 chromosomally normal pregnancies at 15-17 weeks' gestation. Compared to the control pregnancies, both inhibin A and pro-C in

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In second-trimester Down syndrome pregnancies, levels of inhibin-A (the alpha-betaA dimer) in maternal serum and amniotic fluid (AF) are significantly higher and lower than in normal pregnancy, respectively. Since AF also contains inhibin-B (the alpha-betaB dimer) and precursor inhibins, we have exa