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Inheritance of frog lactate dehydrogenase patterns and the persistence of maternal isozymes during development

✍ Scribed by Wright, David A. ;Moyer, Frank H.

Publisher: John Wiley and Sons
Year: 1968
Tongue: English
Weight: 892 KB
Volume: 167
Category: Article
ISSN: 0022-104X
DOI: 10.1002/jez.1401670208

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✦ Synopsis

A female Rana pipiens sphenocephala suspected of being heterozygous at a locus specifying the B or most negatively charged, subunit of the lactate dehydrogenase isozymes was back-crossed to a R . p. sphenocephula male and outcrossed to a R. p. pipiens male. The results of these crosses show that: (1) the structure of the B subunit of frog LDH is controlled by at least three allelic genes (LDB a, LDB b, and LDB "); ( 2 ) LDH of the offsprings' phenotype appears before hatching;

( 3 ) maternal-type enzyme, probably synthesized during oogenesis, persists until at least the eleventh day after the tadpoles begin to feed.

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