While airway rapidly adapting receptors can mediate the cough reflex, much evidence suggests that bronchial C-fibre receptors are also involved in guinea-pigs and man. In man local and systemic C-fibre stimulants have a potent tussive action, which is blocked by low doses of local anaesthetics which
Inhalation Cough Challenge in the Investigation of the Cough Reflex and Antitussives
โ Scribed by A.H. Morice
- Publisher
- Elsevier
- Year
- 1996
- Tongue
- English
- Weight
- 172 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0952-0600
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โฆ Synopsis
Inhalation cough challenge is a useful tool in the physiological and pharmacological investigation of the cough reflex. There are three types of challenge used, capsaicin and the vanilloids, organic acids, and distilled water challenge. In addition, challenge may be administered in a single dose or cumulative dose fashion. The correct combination of inhalation technology and tussive stimulus produces a sensitive and specific method for estimating the cough reflex.
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The causes of right iliac fossa pain are numerous, and it is the presence of localized peritonitis that determines the diagnosis of acute appendicitis. Various tests have been described's2 to elicit intra-abdominal inflammation, with equivocal results3. In this report, an evaluation of the 'cough si