Breast-carcinoma development presumably results from multiple mutational events in tumor-associated genes. Certain results indicate that some tumor-suppressor genes may combine their pathogenetic potential to synergistically promote tumor growth. In an effort to identify such mechanisms in breast tu
โฆ LIBER โฆ
Infrequent Mutation of the H-Cadherin Gene on Chromosome 16q24 in Human Breast Cancers
โ Scribed by Miki, Yoshio ;Katagiri, Toyomasa ;Nakamura, Yusuke
- Book ID
- 108581466
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1997
- Tongue
- English
- Weight
- 295 KB
- Volume
- 88
- Category
- Article
- ISSN
- 0910-5050
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## Human chromosome band 16q24 commonly undergoes loss of heterozygosity (LOH) in human hepatocellular carcinoma (HCC). To further localize the region of deletion on 16q24 and to evaluate the genetic role of 17-beta-HSD, which is near 16q24, in HCC, we examined the pattern of loss of heterozygosity