The analysis of loss of heterozygosity (LOH) in tumours can be a powerful tool for mapping the sites of tumour suppressor genes in the human genome. A panel of breast cancer patients was assembled as pairs of tumour and lymphocyte DNA samples and LOH studies carried out by Southern hybridisation wit
A high-resolution integrated map of the breast cancer loss of heterozygosity region on human chromosome 16q22.1
✍ Scribed by Frengen, Eirik; Rocca-Serra, Philippe; Shaposhnikov, Sergey; Taine, Laurence; Thorsen, Jim; Monéim, Azza Abd El; Longy, Michel; Prydz, Hans; Dorion-Bonnet, Françoise
- Book ID
- 109830401
- Publisher
- Nature Publishing Group
- Year
- 2001
- Tongue
- English
- Weight
- 27 KB
- Volume
- 27
- Category
- Article
- ISSN
- 1061-4036
- DOI
- 10.1038/87080
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