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Infrequent Microsatellite Instability in Urothelial Cell Carcinoma of the Bladder in Young Patients

✍ Scribed by Pierre Mongiat-Artus; Catherine Miquel; Madelon van der Aa; Olivier Buhard; Richard Hamelin; Chris Bangma; Pierre Teillac; Theodorus van der Kwast; Françoise Praz

Book ID
113609123
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
136 KB
Volume
49
Category
Article
ISSN
0302-2838

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Microsatellites may show loss of heterozygosity as well as instability of the repeats. We examined 22 different microsatellites in 14 bladder tumours (7 grade II non-invasive, 7 grade III/IV invasive) and found altered CA repeat length compared with leukocytes, indicating instability, in several mic