Infrequent Ki-ras and an absence of p53 mutations in hepatocellular carcinomas induced by a choline deficient l-amino acid defined diet in rats
✍ Scribed by Toshifumi Tsujiuchi; Akira Kido; Dai Nakae; Makoto Takahama; Toshimitsu Majima; Kunihiko Kobitsu; Eijiro Okajima; Masahiro Tsutsumi; Ayumi Denda; Yoichi Konishi
- Book ID
- 117468336
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 482 KB
- Volume
- 108
- Category
- Article
- ISSN
- 0304-3835
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## Abstract We investigated DNA methylation patterns of E‐cadherin and Connexin26 (Cx26) genes in rat hepatocellular carcinomas (HCCs) induced by a choline‐deficient L‐Amino Acid‐defined (CDAA) diet. Six‐wks‐old F344 male rats were continuously fed with a CDAA diet for 75 wks, and were then killed.
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